Therefore, culture results have been considered as surrogate endpoints for long-term treatment outcome. Collections Theses and Dissertations School of Dentistry. Search for dissertations about: Metagenomic analysis of the human distal gut microbiome. Again, identification of specific pathogen or molecular patterns related to treatment outcome may probably be the best way to establish tests to serve as a more accurate surrogate outcome. While association of E.

Human cytomegalovirus and Epstein-Barr virus in apical and marginal periodontitis: Microorganisms from canals of root-filled teeth with periapical lesions. The disease can manifest clinically in distinct ways and the root canal microbiota may vary accordingly. In advanced stages of the infectious process, bacterial organizations resembling biofilms can be observed adhered to the dentinal root canal walls 9 — 11 Fig. Bacterial reduction and persistence after endodontic treatment procedures.

dissertation apical periodontitis

The treatment may fail in up to 25X of the cases. Enteric rods Olsenella spp. This panel of selected pathogens can then be used against large numbers of clinical samples with reduced cost and time to identify associations with specific disease forms, signs, and symptoms.

Search for dissertations about: “apical periodontitis”

Clinical and radiographic evaluation of one- and two-visit endodontic treatment of asymptomatic necrotic teeth with apical periodontitis: Bacterial reduction apicla persistence after endodontic treatment procedures. Actually, the apical microbiota has been demonstrated to differ significantly periodontitie that occurring in the more coronal aspects of the canal intraindividual analysis in terms of predominant morphotypes 80bacterial community profile 81and anaerobe: Staphylococcus epidermidis and Staphylococcus xylosus in a secondary root canal infection with persistent symptoms: Identification and potential mechanisms of resistance to antimicrobial measures.


Teamwork is what counts — bacterial endodontic communities The last years have witnessed a trend toward a more holistic concept of the etiology of human endogenous infections that considers the bacterial community as the unit of pathogenicity Bacteriology of dental abscesses of endodontic origin. After making a selection, click one of the export format buttons.

As one can see, many issues related to the basic and applied science of endodontic microbiology remain to be addressed. Except for treatment failure, there are no studies in the endodontic literature that have disserfation evaluated the microorganisms associated with these clinical conditions.

The Association of Statin Intake and Healing of Apical Periodontitis After Root Canal Treatment

In addition to frequency of detection, causation may be strengthened on the basis of potential pathogenicity in animal models or deduced from association with other human diseases. Genotypic microbial community profiling: Scand J Dent Res. The relationship of Bacteroides melaninogenicus to symptoms associated with pulpal necrosis.

dissertation apical periodontitis

Community profiling analyses of the endodontic microbiota have disclosed some interesting findings: Inevitably, the concept of endodontic infections as biofilm-arranged communities brings a more holistic view as to the causation of apical periodontitis Quantitative open-ended molecular methods that are more sensitive than culture have the potential to establish more reliable standards to predict outcome.

Patients who self-reported statin use during the treatment and patients who reported never taking statins were included. Molecular identification of microorganisms from endodontic infections.

This discrepancy is better explained by the low sensitivies of culture and microscopic methods and the occurrence of as-yet-uncultivated phylotypes and strains. Molecular identification and quantification of bacteria from endodontic infections using real-time polymerase chain reaction.


dissertation apical periodontitis

A shift in the community structure is then suspected to precede the emergence of symptoms. Show downloadable dissertations only.

Human cytomegalovirus and Epstein-Barr virus in apical and marginal periodontitis: The latter can be explained by the different physico-chemical conditions and type of nutrient availability in the different regions of the canal.

Are dental diseases examples of ecological catastrophes? Interspecies interactions within oral microbial communities.


As early as inMiller 79 emphasized the different morphology of the apical microbiota in comparison to the most coronal microbiota. Differences are essentially represented by different dominant species in the communities and larger number of species in abscesses.

Pseudomonas aeruginosa Prevotella spp.

Even so, one can select 10—20 species that are virtually always among the most frequently detected species in most well-conducted studies about the endodontic microbiota. In terms of bacterial density, a treated canal associated with post-treatment disease can harbor 10 3 —10 7 cells 39, Uncultivated phylotypes from several genera have been identified, including DialisterPrevotellaSynergistesSolobacteriumOlsenellaFusobacteriumEubacteriumMegasphaeraVeillonellaand Selenomonasas well as phylotypes related to the family Lachnospiraceae or the TM7 phylum 2225 — 2865 — Molecular analysis of Filifactor alocis, Tannerella forsythiaand Treponema denticola associated with primary endodontic infections and failed endodontic treatment.

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